研究設備與方法

Research Equipment & Methods

EEG 腦電波儀 Electroencephalography

tDCS/tACS 跨顱電流刺激

tDCS :Transcranial Direct Current Stimulation
tACS:Transcranial Alternating Current Stimulation

tDCS stimulator unit connected to a desktop computer workstation
Electrode placement demonstration on a mannequin head connected to an Eldith stimulator

眼球運動軌跡追蹤儀
Eye Tracker System

Experimental setup with a participant using a chin rest in front of a monitor with an eye-tracking camera & Eye-tracking software interface showing pupil detection and gaze coordinate analysis

TMS 跨顱磁刺激
Transcranial Magnetic Stimulation

Magstim TMS stimulator unit, control screen, and various induction coils on a mobile cart
A researcher applying a figure-eight coil to a participant's head while they perform a task on a tablet

磁刺激導航定位系統
Brainsight Neuronavigation System

Neuronavigation accessories including a pointer and tracking glasses with reflective markers
Wall-mounted infrared tracking camera used to detect spatial coordinates of navigation tools

認知功能虛擬軟硬體設備
HTC VIVE Pro

HTC VIVE Pro VR system kit, including a head-mounted display, two handheld controllers, and two base stations

長距離無線藍芽最大攝氧量測量儀
CORTEX METAMAX 3B

CORTEX METAMAX 3B portable metabolic testing kit inside a foam-padded carrying case, showing sensors, heart rate strap, and accessories

動作捕捉暨動態量測分統
Kinetic Measurement & Analysis System

Infographic of the Kinetic Measurement & Analysis System, showing a person wearing the full sensor suit with detailed specs for the vest, belt, straps, and storage boxes

認知功能訓練/量測應用軟體 APP: 每日腦點心

App icon for Cognitive Function Training, featuring a colorful and stylized brain design
Scan this QR code to access the download page or the Cognitive Function Training App

▾ 研究方法 ▾

HHSA 全息希爾伯特頻譜分析法
Holo-Hilbert Spectral Analysis

HHSA是以黃鍔院士於1998年發明之Hilbert-Huang transform(HHT)為基礎,配合認知神經科學和腦科學研究所取得的大量研究數據,進行反覆試算、優化以及驗證,進一步開發出全新的HHSA非線性動態數據分析方法,HHT可以有效改善傳統線性分析方法的不足,已被廣泛地運用在生物訊號、血壓變化和心律不整、地球物理探測、地震工程、結構損害偵測等研究上,在1998年發表的HHT原始論文著作迄今已被引用超過26,800次(Google Scholar)。然而,HHT雖然可分析出非線性訊號中的許多重要資訊,但是仍無法解決三維或多維的非線性及非穩態資料交互作用的問題。HHSA能夠高維資料形式正確揭露神經訊號中不同頻段因相乘而產生的非線性作用,以及相同頻段中因振幅不同而產生的調節作用,是以能夠反映出腦系統中複雜的非線性與非穩態之全面向性的神經活動。 本團隊於2016年將自行開發的HHSA方法發表在Philosophical Transactions of The Royal Society A: Mathematical, Physical and Engineering Sciences期刊;本研究成果以該方法突破傳統分析方法難以有效解析非線性和非穩態數據的瓶頸,取得革命性的創新進展。

Scientific research figure illustrating the Holo-Hilbert Spectral Analysis (HHSA) method. Panel A compares Fourier and Holo-Hilbert spectra; Panel B shows signal decomposition with HHT vs HHS; Panel C details interareal neural coupling and connectivity across cognitive phases.

研究團隊以HHSA探討認知功能之非線性及動態神經機制的相關研究成果 (Juan et al., 2021;Liang et al., 2021;Nguyen et al., 2019),(A)解析穩態視覺誘發電位誘發之腦波訊號,驗證了HHSA能凌駕傳統傅立葉轉換分析方法,(B)並有效解析訊號非線性的動態特徵。此外,(C)HHSA衍伸之功能性神經振盪聯絡分析方法應用於工作記憶研究,發現theta相位與beta振幅振盪頻率為工作記憶關鍵神經振盪聯絡。

Skip to content